Inhibition of Hepatitis C Virus Infection by DNA Aptamer against NS2 Protein

NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and antiviral effects of the aptamers were examined. The molecular mechanism through which the aptamers exert their anti-HCV activity was investigated. T...

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Detalles Bibliográficos
Autores principales: Gao, Yimin, Yu, Xiaoyan, Xue, Binbin, Zhou, Fei, Wang, Xiaohong, Yang, Darong, Liu, Nianli, Xu, Li, Fang, Xiaohong, Zhu, Haizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938669/
https://www.ncbi.nlm.nih.gov/pubmed/24587329
http://dx.doi.org/10.1371/journal.pone.0090333

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