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Protein Tyrosine Phosphatase-1B Modulates Pancreatic β-cell Mass
Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of the insulin signalling pathway. It has been demonstrated that PTP1B deletion protects against the development of obesity and Type 2 Diabetes, mainly through its action on peripheral tissues. However, little attention has been paid to...
Autores principales: | Fernandez-Ruiz, Rebeca, Vieira, Elaine, Garcia-Roves, Pablo M., Gomis, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938680/ https://www.ncbi.nlm.nih.gov/pubmed/24587334 http://dx.doi.org/10.1371/journal.pone.0090344 |
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