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Protein Tyrosine Phosphatase-1B Modulates Pancreatic β-cell Mass

Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of the insulin signalling pathway. It has been demonstrated that PTP1B deletion protects against the development of obesity and Type 2 Diabetes, mainly through its action on peripheral tissues. However, little attention has been paid to...

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Detalles Bibliográficos
Autores principales: Fernandez-Ruiz, Rebeca, Vieira, Elaine, Garcia-Roves, Pablo M., Gomis, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938680/
https://www.ncbi.nlm.nih.gov/pubmed/24587334
http://dx.doi.org/10.1371/journal.pone.0090344

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