An mDia2/ROCK Signaling Axis Regulates Invasive Egress from Epithelial Ovarian Cancer Spheroids

Multi-cellular spheroids are enriched in ascites of epithelial ovarian cancer (OvCa) patients. They represent an invasive and chemoresistant cellular population fundamental to metastatic dissemination. The molecular mechanisms triggering single cell invasive egress from spheroids remain enigmatic. m...

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Detalles Bibliográficos
Autores principales: Pettee, Krista M., Dvorak, Kaitlyn M., Nestor-Kalinoski, Andrea L., Eisenmann, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938721/
https://www.ncbi.nlm.nih.gov/pubmed/24587343
http://dx.doi.org/10.1371/journal.pone.0090371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938721/
https://www.ncbi.nlm.nih.gov/pubmed/24587343
http://dx.doi.org/10.1371/journal.pone.0090371

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