Optimization and In Vivo Toxicity Evaluation of G4.5 Pamam Dendrimer-Risperidone Complexes

Risperidone is an approved antipsychotic drug belonging to the chemical class of benzisoxazole. This drug has low solubility in aqueous medium and poor bioavailability due to extensive first-pass metabolism and high protein binding (>90%). Since new strategies to improve efficient treatments are...

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Detalles Bibliográficos
Autores principales: Prieto, Maria Jimena, del Rio Zabala, Nahuel Eduardo, Marotta, Cristian Hernán, Carreño Gutierrez, Hector, Arévalo Arévalo, Rosario, Chiaramoni, Nadia Silvia, Alonso, Silvia del Valle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938724/
https://www.ncbi.nlm.nih.gov/pubmed/24587349
http://dx.doi.org/10.1371/journal.pone.0090393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938724/
https://www.ncbi.nlm.nih.gov/pubmed/24587349
http://dx.doi.org/10.1371/journal.pone.0090393

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