Selection for Phase Variation of LOS Biosynthetic Genes Frequently Occurs in Progression of Non-Typeable Haemophilus influenzae Infection from the Nasopharynx to the Middle Ear of Human Patients

Surface structures in Haemophilus influenzae are subject to rapid ON/OFF switching of expression, a process termed phase variation. We analyse tetranucleotide repeats controlling phase variation in lipo-oligosaccharide (LOS) genes of H. influenzae in paired isolates from both the nasopharynx and mid...

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Detalles Bibliográficos
Autores principales: Fox, Kate L., Atack, John M., Srikhanta, Yogitha N., Eckert, Anja, Novotny, Laura A., Bakaletz, Lauren O., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938747/
https://www.ncbi.nlm.nih.gov/pubmed/24587383
http://dx.doi.org/10.1371/journal.pone.0090505

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