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Beneficial Antimicrobial Effect of the Addition of an Aminoglycoside to a β-Lactam Antibiotic in an E. coli Porcine Intensive Care Severe Sepsis Model
This study aimed to determine whether the addition of an aminoglycoside to a ß-lactam antibiotic increases the antimicrobial effect during the early phase of Gram-negative severe sepsis/septic shock. A porcine model was selected that considered each animal’s individual blood bactericidal capacity. E...
Autores principales: | Skorup, Paul, Maudsdotter, Lisa, Lipcsey, Miklós, Castegren, Markus, Larsson, Anders, Jonsson, Ann-Beth, Sjölin, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938751/ https://www.ncbi.nlm.nih.gov/pubmed/24587365 http://dx.doi.org/10.1371/journal.pone.0090441 |
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