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A Model of Proteostatic Energy Cost and Its Use in Analysis of Proteome Trends and Sequence Evolution
A model of proteome-associated chemical energetic costs of cells is derived from protein-turnover kinetics and protein folding. Minimization of the proteostatic maintenance cost can explain a range of trends of proteomes and combines both protein function, stability, size, proteostatic cost, tempera...
Autores principales: | Kepp, Kasper P., Dasmeh, Pouria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938754/ https://www.ncbi.nlm.nih.gov/pubmed/24587382 http://dx.doi.org/10.1371/journal.pone.0090504 |
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