Reducing ppGpp Level Rescues an Extreme Growth Defect Caused by Mutant EF-Tu

Transcription and translation of mRNA's are coordinated processes in bacteria. We have previously shown that a mutant form of EF-Tu (Gln125Arg) in Salmonella Typhimurium with a reduced affinity for aa-tRNA, causes ribosome pausing, resulting in an increased rate of RNase E-mediated mRNA cleavag...

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Detalles Bibliográficos
Autores principales: Bergman, Jessica M., Hammarlöf, Disa L., Hughes, Diarmaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938759/
https://www.ncbi.nlm.nih.gov/pubmed/24587376
http://dx.doi.org/10.1371/journal.pone.0090486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938759/
https://www.ncbi.nlm.nih.gov/pubmed/24587376
http://dx.doi.org/10.1371/journal.pone.0090486

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