Extra-Cellular Matrix Proteins Induce Matrix Metalloproteinase-1 (MMP-1) Activity and Increase Airway Smooth Muscle Contraction in Asthma

Airway remodelling describes the histopathological changes leading to fixed airway obstruction in patients with asthma and includes extra-cellular matrix (ECM) deposition. Matrix metalloproteinase-1 (MMP-1) is present in remodelled airways but its relationship with ECM proteins and the resulting fun...

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Detalles Bibliográficos
Autores principales: Rogers, Natasha K., Clements, Debbie, Dongre, Arundhati, Harrison, Tim W., Shaw, Dominic, Johnson, Simon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938782/
https://www.ncbi.nlm.nih.gov/pubmed/24587395
http://dx.doi.org/10.1371/journal.pone.0090565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938782/
https://www.ncbi.nlm.nih.gov/pubmed/24587395
http://dx.doi.org/10.1371/journal.pone.0090565

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