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Extra-Cellular Matrix Proteins Induce Matrix Metalloproteinase-1 (MMP-1) Activity and Increase Airway Smooth Muscle Contraction in Asthma

Airway remodelling describes the histopathological changes leading to fixed airway obstruction in patients with asthma and includes extra-cellular matrix (ECM) deposition. Matrix metalloproteinase-1 (MMP-1) is present in remodelled airways but its relationship with ECM proteins and the resulting fun...

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Detalles Bibliográficos
Autores principales:	Rogers, Natasha K., Clements, Debbie, Dongre, Arundhati, Harrison, Tim W., Shaw, Dominic, Johnson, Simon R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938782/ https://www.ncbi.nlm.nih.gov/pubmed/24587395 http://dx.doi.org/10.1371/journal.pone.0090565

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