Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()

A 10-year-old boy presented with headache and visual disturbance. During work-up in hospital he developed acute renal failure with a maximum creatinine level of 534 μmol/l. Complete blood count was normal. Kidney and bone marrow biopsy both showed massive infiltration of lymphoblasts of T-cell linag...

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Detalles Bibliográficos
Autores principales: Asdahl, Peter H., Warner, Linda F., Bendix, Knud, Hasle, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939384/
https://www.ncbi.nlm.nih.gov/pubmed/24596675
http://dx.doi.org/10.1016/j.lrr.2013.11.002
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author Asdahl, Peter H.
Warner, Linda F.
Bendix, Knud
Hasle, Henrik
author_facet Asdahl, Peter H.
Warner, Linda F.
Bendix, Knud
Hasle, Henrik
author_sort Asdahl, Peter H.
collection PubMed
description A 10-year-old boy presented with headache and visual disturbance. During work-up in hospital he developed acute renal failure with a maximum creatinine level of 534 μmol/l. Complete blood count was normal. Kidney and bone marrow biopsy both showed massive infiltration of lymphoblasts of T-cell linage. Renal function normalized rapidly on prednisolone therapy. Kidney involvement in acute lymphoblastic leukemia is uncommon and renal failure due to leukemic infiltration is only sporadically reported. This case emphasizes the importance of kidney and bone marrow biopsy in cases of unexplained acute renal failure even with normal hematology.
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spelling pubmed-39393842014-03-04 Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia() Asdahl, Peter H. Warner, Linda F. Bendix, Knud Hasle, Henrik Leuk Res Rep Case Report A 10-year-old boy presented with headache and visual disturbance. During work-up in hospital he developed acute renal failure with a maximum creatinine level of 534 μmol/l. Complete blood count was normal. Kidney and bone marrow biopsy both showed massive infiltration of lymphoblasts of T-cell linage. Renal function normalized rapidly on prednisolone therapy. Kidney involvement in acute lymphoblastic leukemia is uncommon and renal failure due to leukemic infiltration is only sporadically reported. This case emphasizes the importance of kidney and bone marrow biopsy in cases of unexplained acute renal failure even with normal hematology. Elsevier 2013-12-08 /pmc/articles/PMC3939384/ /pubmed/24596675 http://dx.doi.org/10.1016/j.lrr.2013.11.002 Text en © 2013 The Authors http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Asdahl, Peter H.
Warner, Linda F.
Bendix, Knud
Hasle, Henrik
Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()
title Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()
title_full Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()
title_fullStr Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()
title_full_unstemmed Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()
title_short Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia()
title_sort acute renal failure and normal blood count: a rare presentation of t-cell acute lymphoblastic leukemia()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939384/
https://www.ncbi.nlm.nih.gov/pubmed/24596675
http://dx.doi.org/10.1016/j.lrr.2013.11.002
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AT haslehenrik acuterenalfailureandnormalbloodcountararepresentationoftcellacutelymphoblasticleukemia

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