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Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom

Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation o...

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Autores principales: Jameson, Lisa J., Newton, Autilia, Coole, Louise, Newman, Edmund N. C., Carroll, Miles W., Beeching, Nick J., Hewson, Roger, Christley, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939470/
https://www.ncbi.nlm.nih.gov/pubmed/24504130
http://dx.doi.org/10.3390/v6020524
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author Jameson, Lisa J.
Newton, Autilia
Coole, Louise
Newman, Edmund N. C.
Carroll, Miles W.
Beeching, Nick J.
Hewson, Roger
Christley, Robert M.
author_facet Jameson, Lisa J.
Newton, Autilia
Coole, Louise
Newman, Edmund N. C.
Carroll, Miles W.
Beeching, Nick J.
Hewson, Roger
Christley, Robert M.
author_sort Jameson, Lisa J.
collection PubMed
description Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation of a Seoul hantavirus from rats trapped on the patient’s farm, it was considered appropriate to further investigate the public health risk of this virus in the region. Of a total 119 individuals tested, nine (7.6%) were seropositive for hantavirus antibodies. Seven of the seropositive samples showed a stronger reaction to Seoul and Hantaan compared to other clinically relevant hantaviruses. Observation of rodents during the day, in particular mice, was associated with a reduced risk of seropositivity. In addition to one region known to be at risk following an acute case, five further potential risk areas have been identified. This study supports recently published evidence that hantaviruses are likely to be of public health interest in the region.
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spelling pubmed-39394702014-03-03 Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom Jameson, Lisa J. Newton, Autilia Coole, Louise Newman, Edmund N. C. Carroll, Miles W. Beeching, Nick J. Hewson, Roger Christley, Robert M. Viruses Article Hantaviruses are an established cause of haemorrhagic fever with renal syndrome (HFRS) in Europe. Following a confirmed case of HFRS in the UK, in an individual residing on a farm in North Yorkshire and the Humber, a tidal estuary on the east coast of Northern England, and the subsequent isolation of a Seoul hantavirus from rats trapped on the patient’s farm, it was considered appropriate to further investigate the public health risk of this virus in the region. Of a total 119 individuals tested, nine (7.6%) were seropositive for hantavirus antibodies. Seven of the seropositive samples showed a stronger reaction to Seoul and Hantaan compared to other clinically relevant hantaviruses. Observation of rodents during the day, in particular mice, was associated with a reduced risk of seropositivity. In addition to one region known to be at risk following an acute case, five further potential risk areas have been identified. This study supports recently published evidence that hantaviruses are likely to be of public health interest in the region. MDPI 2014-02-05 /pmc/articles/PMC3939470/ /pubmed/24504130 http://dx.doi.org/10.3390/v6020524 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Jameson, Lisa J.
Newton, Autilia
Coole, Louise
Newman, Edmund N. C.
Carroll, Miles W.
Beeching, Nick J.
Hewson, Roger
Christley, Robert M.
Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom
title Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom
title_full Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom
title_fullStr Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom
title_full_unstemmed Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom
title_short Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom
title_sort prevalence of antibodies against hantaviruses in serum and saliva of adults living or working on farms in yorkshire, united kingdom
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939470/
https://www.ncbi.nlm.nih.gov/pubmed/24504130
http://dx.doi.org/10.3390/v6020524
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