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Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair

By directed evolution in the laboratory, we previously generated populations of Escherichia coli that exhibit a complex new phenotype, extreme resistance to ionizing radiation (IR). The molecular basis of this extremophile phenotype, involving strain isolates with a 3-4 order of magnitude increase i...

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Detalles Bibliográficos
Autores principales: Byrne, Rose T, Klingele, Audrey J, Cabot, Eric L, Schackwitz, Wendy S, Martin, Jeffrey A, Martin, Joel, Wang, Zhong, Wood, Elizabeth A, Pennacchio, Christa, Pennacchio, Len A, Perna, Nicole T, Battista, John R, Cox, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939492/
https://www.ncbi.nlm.nih.gov/pubmed/24596148
http://dx.doi.org/10.7554/eLife.01322