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Immune Responses to AAV-Vectors, the Glybera Example from Bench to Bedside

Alipogene tiparvovec (Glybera(®)) is an adeno-associated virus serotype 1 (AAV1)-based gene therapy that has been developed for the treatment of patients with lipoprotein lipase (LPL) deficiency. Alipogene tiparvovec contains the human LPL naturally occurring gene variant LPL(S447X) in a non-replica...

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Detalles Bibliográficos
Autores principales:	Ferreira, Valerie, Petry, Harald, Salmon, Florence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939780/ https://www.ncbi.nlm.nih.gov/pubmed/24624131 http://dx.doi.org/10.3389/fimmu.2014.00082

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