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Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes

We aimed to assess the association between skin thickness and glycaemic control in children with type 1 diabetes. Forty-five children (51% males) aged 10.5 ± 2.1 years were studied. Thickness of skin layers were determined by ultrasonography, with participants having ultrasound scans of three anatom...

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Autores principales: Derraik, José G B, Rademaker, Marius, Cutfield, Wayne S, Peart, Jane M, Jefferies, Craig, Hofman, Paul L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939813/
https://www.ncbi.nlm.nih.gov/pubmed/24576336
http://dx.doi.org/10.1186/1687-9856-2014-2
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author Derraik, José G B
Rademaker, Marius
Cutfield, Wayne S
Peart, Jane M
Jefferies, Craig
Hofman, Paul L
author_facet Derraik, José G B
Rademaker, Marius
Cutfield, Wayne S
Peart, Jane M
Jefferies, Craig
Hofman, Paul L
author_sort Derraik, José G B
collection PubMed
description We aimed to assess the association between skin thickness and glycaemic control in children with type 1 diabetes. Forty-five children (51% males) aged 10.5 ± 2.1 years were studied. Thickness of skin layers were determined by ultrasonography, with participants having ultrasound scans of three anatomical regions (abdomen, thigh, and buttocks). Poorer glycaemic control (increasing HbA1c values) was associated with greater thickness of the dermis (p = 0.015), with an estimated thickening of 87 μm with every 1% increase in HbA1c. Our data suggest that dermal changes associated with poorer glycaemic control in adults are also observed in childhood.
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spelling pubmed-39398132014-03-04 Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes Derraik, José G B Rademaker, Marius Cutfield, Wayne S Peart, Jane M Jefferies, Craig Hofman, Paul L Int J Pediatr Endocrinol Letter to the Editor We aimed to assess the association between skin thickness and glycaemic control in children with type 1 diabetes. Forty-five children (51% males) aged 10.5 ± 2.1 years were studied. Thickness of skin layers were determined by ultrasonography, with participants having ultrasound scans of three anatomical regions (abdomen, thigh, and buttocks). Poorer glycaemic control (increasing HbA1c values) was associated with greater thickness of the dermis (p = 0.015), with an estimated thickening of 87 μm with every 1% increase in HbA1c. Our data suggest that dermal changes associated with poorer glycaemic control in adults are also observed in childhood. BioMed Central 2014 2014-02-27 /pmc/articles/PMC3939813/ /pubmed/24576336 http://dx.doi.org/10.1186/1687-9856-2014-2 Text en Copyright © 2014 Derraik et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Derraik, José G B
Rademaker, Marius
Cutfield, Wayne S
Peart, Jane M
Jefferies, Craig
Hofman, Paul L
Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
title Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
title_full Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
title_fullStr Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
title_full_unstemmed Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
title_short Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
title_sort poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939813/
https://www.ncbi.nlm.nih.gov/pubmed/24576336
http://dx.doi.org/10.1186/1687-9856-2014-2
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