Cargando…
Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12
The extensive set of NMR doublings exhibited by the immunophilin FKBP12 (FK506-binding protein 12) arose from a slow transition to the cis-peptide configuration at Gly(89) near the tip of the 80′s loop, the site for numerous protein-recognition interactions for both FKBP12 and other FKBP domain prot...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940039/ https://www.ncbi.nlm.nih.gov/pubmed/24405377 http://dx.doi.org/10.1042/BJ20131429 |