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Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites()

Aminoacyl-tRNA synthetases are central enzymes in protein translation, providing the charged tRNAs needed for appropriate construction of peptide chains. These enzymes have long been pursued as drug targets in bacteria and fungi, but the past decade has seen considerable research on aminoacyl-tRNA s...

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Detalles Bibliográficos
Autores principales: Pham, James S., Dawson, Karen L., Jackson, Katherine E., Lim, Erin E., Pasaje, Charisse Flerida A., Turner, Kelsey E.C., Ralph, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940080/
https://www.ncbi.nlm.nih.gov/pubmed/24596663
http://dx.doi.org/10.1016/j.ijpddr.2013.10.001

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