Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism()

There are many theories as to the mode of action of miltefosine against Leishmania including alterations to the membrane lipid content, induction of apoptosis and modulation of macrophage responses. Here we perform untargeted metabolomics to elucidate the metabolic changes involved in miltefosine ac...

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Detalles Bibliográficos
Autores principales: Vincent, Isabel M., Weidt, Stefan, Rivas, Luis, Burgess, Karl, Smith, Terry K., Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940234/
https://www.ncbi.nlm.nih.gov/pubmed/24596665
http://dx.doi.org/10.1016/j.ijpddr.2013.11.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940234/
https://www.ncbi.nlm.nih.gov/pubmed/24596665
http://dx.doi.org/10.1016/j.ijpddr.2013.11.002

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