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ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48

ORM (yeast)-Like protein isoform 3 (ORMDL3) has recently been identified as a candidate gene for susceptibility to asthma; however the mechanisms by which it contributes to asthma pathogenesis are not well understood. Here we demonstrate a functional role for ORMDL3 in eosinophils in the context of...

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Detalles Bibliográficos
Autores principales: Ha, Sung Gil, Ge, Xiao Na, Bahaie, Nooshin S., Kang, Bit Na, Rao, Amrita, Rao, Savita P., Sriramarao, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940275/
https://www.ncbi.nlm.nih.gov/pubmed/24056518
http://dx.doi.org/10.1038/ncomms3479

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