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ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48
ORM (yeast)-Like protein isoform 3 (ORMDL3) has recently been identified as a candidate gene for susceptibility to asthma; however the mechanisms by which it contributes to asthma pathogenesis are not well understood. Here we demonstrate a functional role for ORMDL3 in eosinophils in the context of...
Autores principales: | Ha, Sung Gil, Ge, Xiao Na, Bahaie, Nooshin S., Kang, Bit Na, Rao, Amrita, Rao, Savita P., Sriramarao, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940275/ https://www.ncbi.nlm.nih.gov/pubmed/24056518 http://dx.doi.org/10.1038/ncomms3479 |
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