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Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis
BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by ovarian enlargement, hyperplastic theca compartment and increased androgen production due to, at least in part, excessive expression of several key genes involved in steroidogenesis. Previously, our group has demonstrated that simvasta...
Autores principales: | Ortega, Israel, Villanueva, Jesus A, Wong, Donna H, Cress, Amanda B, Sokalska, Anna, Stanley, Scott D, Duleba, Antoni J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940290/ https://www.ncbi.nlm.nih.gov/pubmed/24524197 http://dx.doi.org/10.1186/1757-2215-7-21 |
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