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Superoxide dismutase analog (TEMPOL: 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) treatment restores erectile function in diabetes-induced impotence

We hypothesized that administration of the superoxide dismutase (SOD) mimetic Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) may reverse diabetes induced ED(erectile dysfunction). To test this hypothesis, ROS related genes (SOD1, SOD2, GPx1, CAT, NOS2, NOS3), erectile functional studies,...

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Detalles Bibliográficos
Autores principales: Kawakami, Toshifumi, Urakami, Shinji, Hirata, Hiroshi, Tanaka, Yuichiro, Nakajima, Koichi, Enokida, Hideki, Shiina, Hiroaki, Ogishima, Tatsuya, Tokizane, Takashi, Kawamoto, Ken, Miura, Kazukiyo, Ishii, Nobuhisa, Dahiya, Rajvir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940356/
https://www.ncbi.nlm.nih.gov/pubmed/19554009
http://dx.doi.org/10.1038/ijir.2009.28

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