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Superoxide dismutase analog (TEMPOL: 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) treatment restores erectile function in diabetes-induced impotence
We hypothesized that administration of the superoxide dismutase (SOD) mimetic Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) may reverse diabetes induced ED(erectile dysfunction). To test this hypothesis, ROS related genes (SOD1, SOD2, GPx1, CAT, NOS2, NOS3), erectile functional studies,...
Autores principales: | Kawakami, Toshifumi, Urakami, Shinji, Hirata, Hiroshi, Tanaka, Yuichiro, Nakajima, Koichi, Enokida, Hideki, Shiina, Hiroaki, Ogishima, Tatsuya, Tokizane, Takashi, Kawamoto, Ken, Miura, Kazukiyo, Ishii, Nobuhisa, Dahiya, Rajvir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940356/ https://www.ncbi.nlm.nih.gov/pubmed/19554009 http://dx.doi.org/10.1038/ijir.2009.28 |
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