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Admixture Mapping and Subsequent Fine-Mapping Suggests a Biologically Relevant and Novel Association on Chromosome 11 for Type 2 Diabetes in African Americans
Type 2 diabetes (T2D) is a complex metabolic disease that disproportionately affects African Americans. Genome-wide association studies (GWAS) have identified several loci that contribute to T2D in European Americans, but few studies have been performed in admixed populations. We first performed a G...
Autores principales: | Jeff, Janina M., Armstrong, Loren L., Ritchie, Marylyn D., Denny, Joshua C., Kho, Abel N., Basford, Melissa A., Wolf, Wendy A., Pacheco, Jennifer A., Li, Rongling, Chisholm, Rex L., Roden, Dan M., Hayes, M. Geoffrey, Crawford, Dana C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940426/ https://www.ncbi.nlm.nih.gov/pubmed/24595071 http://dx.doi.org/10.1371/journal.pone.0086931 |
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