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Inhibition of Gsk3β activity improves β-cell function in c-Kit(Wv/+) male mice
Previous studies have shown that the stem cell marker, c-Kit, is involved in glucose homeostasis. We recently reported that c-Kit(Wv/+) male mice displayed onset of diabetes at 8 weeks of age; however, the mechanisms by which c-Kit regulates β-cell proliferation and function are unknown. The purpose...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940483/ https://www.ncbi.nlm.nih.gov/pubmed/22249311 http://dx.doi.org/10.1038/labinvest.2011.200 |