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Germline genetic variants in ABCB1, ABCC1, and ALDH1A1 and risk of hematological and gastrointestinal toxicities in a SWOG Phase III trial S0221 for breast cancer

Hematological and gastrointestinal toxicities are common among patients treated with cyclophosphamide and doxorubicin for breast cancer. To examine whether single nucleotide polymorphisms (SNPs) in key pharmacokinetic genes were associated with risk of hematological or gastrointestinal toxicity, we...

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Detalles Bibliográficos
Autores principales:	Yao, Song, Sucheston, Lara E., Zhao, Hua, Barlow, William E., Zirpoli, Gary, Liu, Song, Moore, Halle C.F., Budd, G. Thomas, Hershman, Dawn L., Davis, Warren, Ciupak, Gregory L., Stewart, James A., Isaacs, Claudine, Hobday, Timothy J., Salim, Muhammad, Hortobagyi, Gabriel N., Gralow, Julie R., Livingston, Robert B., Albain, Kathy S., Hayes, Daniel F., Ambrosone, Christine B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940691/ https://www.ncbi.nlm.nih.gov/pubmed/23999597 http://dx.doi.org/10.1038/tpj.2013.32

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