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Interaction between Transactivation Domain of p53 and Middle Part of TBP-Like Protein (TLP) Is Involved in TLP-Stimulated and p53-Activated Transcription from the p21 Upstream Promoter

TBP-like protein (TLP) is involved in transcriptional activation of an upstream promoter of the human p21 gene. TLP binds to p53 and facilitates p53-activated transcription from the upstream promoter. In this study, we clarified that in vitro affinity between TLP and p53 is about one-third of that b...

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Detalles Bibliográficos
Autores principales: Maeda, Ryo, Suzuki, Hidefumi, Tanaka, Yuta, Tamura, Taka-aki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940844/
https://www.ncbi.nlm.nih.gov/pubmed/24594805
http://dx.doi.org/10.1371/journal.pone.0090190