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Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties

We have investigated some roles of splicing factor polypyrimidine tract-binding protein (PTBP1) in human breast cancer. We found that PTBP1 was upregulated in progressively transformed human mammary epithelial cells (HMECs), as well as in breast tumor cell lines compared with HMECs with finite growt...

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Detalles Bibliográficos
Autores principales: He, X, Arslan, A D, Ho, T-T, Yuan, C, Stampfer, M R, Beck, W T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940912/
https://www.ncbi.nlm.nih.gov/pubmed/24418892
http://dx.doi.org/10.1038/oncsis.2013.47