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Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies

Soluble oligomeric assemblies of amyloidal proteins appear to act as major pathological agents in several degenerative disorders. Isolation and characterization of these oligomers is a pivotal step towards determination of their pathological relevance. Here we describe the isolation of Type 2 diabet...

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Detalles Bibliográficos
Autores principales: Bram, Yaron, Frydman-Marom, Anat, Yanai, Inbal, Gilead, Sharon, Shaltiel-Karyo, Ronit, Amdursky, Nadav, Gazit, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940978/
https://www.ncbi.nlm.nih.gov/pubmed/24589570
http://dx.doi.org/10.1038/srep04267

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