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Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies
Soluble oligomeric assemblies of amyloidal proteins appear to act as major pathological agents in several degenerative disorders. Isolation and characterization of these oligomers is a pivotal step towards determination of their pathological relevance. Here we describe the isolation of Type 2 diabet...
Autores principales: | Bram, Yaron, Frydman-Marom, Anat, Yanai, Inbal, Gilead, Sharon, Shaltiel-Karyo, Ronit, Amdursky, Nadav, Gazit, Ehud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940978/ https://www.ncbi.nlm.nih.gov/pubmed/24589570 http://dx.doi.org/10.1038/srep04267 |
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