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CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

mTORC1 (mammalian target of rapamycin complex 1) integrates information regarding availability of nutrients and energy to coordinate protein synthesis and autophagy. Using ribonucleic acid interference screens for autophagy-regulating phosphatases in human breast cancer cells, we identify CIP2A (can...

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Detalles Bibliográficos
Autores principales:	Puustinen, Pietri, Rytter, Anna, Mortensen, Monika, Kohonen, Pekka, Moreira, José M., Jäättelä, Marja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941044/ https://www.ncbi.nlm.nih.gov/pubmed/24590173 http://dx.doi.org/10.1083/jcb.201304012

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