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Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner

Munc18-1 is a soluble protein essential for synaptic transmission. To investigate the dynamics of endogenous Munc18-1 in neurons, we created a mouse model expressing fluorescently tagged Munc18-1 from the endogenous munc18-1 locus. We show using fluorescence recovery after photobleaching in hippocam...

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Detalles Bibliográficos
Autores principales:	Cijsouw, Tony, Weber, Jens P., Broeke, Jurjen H., Broek, Jantine A.C., Schut, Desiree, Kroon, Tim, Saarloos, Ingrid, Verhage, Matthijs, Toonen, Ruud F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941046/ https://www.ncbi.nlm.nih.gov/pubmed/24590174 http://dx.doi.org/10.1083/jcb.201308026

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