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Twist1-induced dissemination preserves epithelial identity and requires E-cadherin
Dissemination of epithelial cells is a critical step in metastatic spread. Molecular models of dissemination focus on loss of E-cadherin or repression of cell adhesion through an epithelial to mesenchymal transition (EMT). We sought to define the minimum molecular events necessary to induce dissemin...
Autores principales: | Shamir, Eliah R., Pappalardo, Elisa, Jorgens, Danielle M., Coutinho, Kester, Tsai, Wen-Ting, Aziz, Khaled, Auer, Manfred, Tran, Phuoc T., Bader, Joel S., Ewald, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941052/ https://www.ncbi.nlm.nih.gov/pubmed/24590176 http://dx.doi.org/10.1083/jcb.201306088 |
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