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Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells
SAS-6 proteins are thought to impart the ninefold symmetry of centrioles, but the mechanisms by which their assembly occurs within cells remain elusive. In this paper, we provide evidence that the N-terminal, coiled-coil, and C-terminal domains of HsSAS-6 are each required for procentriole formation...
Autores principales: | Keller, Debora, Orpinell, Meritxell, Olivier, Nicolas, Wachsmuth, Malte, Mahen, Robert, Wyss, Romain, Hachet, Virginie, Ellenberg, Jan, Manley, Suliana, Gönczy, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941056/ https://www.ncbi.nlm.nih.gov/pubmed/24590172 http://dx.doi.org/10.1083/jcb.201307049 |
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