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A mobile insulator system to detect and disrupt cis-regulatory landscapes in vertebrates
In multicellular organisms, cis-regulation controls gene expression in space and time. Despite the essential implication of cis-regulation in the development and evolution of organisms and in human diseases, our knowledge about regulatory sequences largely derives from analyzing their activity indiv...
Autores principales: | Bessa, José, Luengo, Mario, Rivero-Gil, Solangel, Ariza-Cosano, Ana, Maia, António H.F., Ruiz-Ruano, Francisco J., Caballero, Pablo, Naranjo, Silvia, Carvajal, Jaime J., Gómez-Skarmeta, José Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941113/ https://www.ncbi.nlm.nih.gov/pubmed/24277716 http://dx.doi.org/10.1101/gr.165654.113 |
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