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Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic

The objective of this review was to evaluate the clinical efficacy and safety of remifentanil in the management of labor pain. Although neuraxial analgesia is the best option during labor, alternative analgesic options are needed for patients with contraindications. Using a systematic literature sea...

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Autor principal: Devabhakthuni, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941183/
https://www.ncbi.nlm.nih.gov/pubmed/24665213
http://dx.doi.org/10.4137/CMWH.S8015
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author Devabhakthuni, Sandeep
author_facet Devabhakthuni, Sandeep
author_sort Devabhakthuni, Sandeep
collection PubMed
description The objective of this review was to evaluate the clinical efficacy and safety of remifentanil in the management of labor pain. Although neuraxial analgesia is the best option during labor, alternative analgesic options are needed for patients with contraindications. Using a systematic literature search, clinical outcomes of remifentanil for labor pain have been summarized. Also, comparisons of remifentanil to other options including meperidine, epidural analgesia, fentanyl, and nitrous oxide are provided. Based on the literature review, remifentanil is associated with high overall maternal satisfaction and favorable side-effect profile. However, due to the low reporting of adverse events, large, randomized controlled trials are needed to evaluate maternal and neonatal safety adequately and determine the optimal dosing needed to provide effective analgesia. While remifentanil is a feasible alternative for patients who cannot or do not want to receive epidural analgesia, administration should be monitored closely for potential adverse effects.
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spelling pubmed-39411832014-03-24 Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic Devabhakthuni, Sandeep Clin Med Insights Womens Health The objective of this review was to evaluate the clinical efficacy and safety of remifentanil in the management of labor pain. Although neuraxial analgesia is the best option during labor, alternative analgesic options are needed for patients with contraindications. Using a systematic literature search, clinical outcomes of remifentanil for labor pain have been summarized. Also, comparisons of remifentanil to other options including meperidine, epidural analgesia, fentanyl, and nitrous oxide are provided. Based on the literature review, remifentanil is associated with high overall maternal satisfaction and favorable side-effect profile. However, due to the low reporting of adverse events, large, randomized controlled trials are needed to evaluate maternal and neonatal safety adequately and determine the optimal dosing needed to provide effective analgesia. While remifentanil is a feasible alternative for patients who cannot or do not want to receive epidural analgesia, administration should be monitored closely for potential adverse effects. Libertas Academica 2013-05-06 /pmc/articles/PMC3941183/ /pubmed/24665213 http://dx.doi.org/10.4137/CMWH.S8015 Text en © 2013 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Devabhakthuni, Sandeep
Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
title Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
title_full Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
title_fullStr Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
title_full_unstemmed Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
title_short Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
title_sort efficacy and safety of remifentanil as an alternative labor analgesic
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941183/
https://www.ncbi.nlm.nih.gov/pubmed/24665213
http://dx.doi.org/10.4137/CMWH.S8015
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