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Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic
The objective of this review was to evaluate the clinical efficacy and safety of remifentanil in the management of labor pain. Although neuraxial analgesia is the best option during labor, alternative analgesic options are needed for patients with contraindications. Using a systematic literature sea...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941183/ https://www.ncbi.nlm.nih.gov/pubmed/24665213 http://dx.doi.org/10.4137/CMWH.S8015 |
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author | Devabhakthuni, Sandeep |
author_facet | Devabhakthuni, Sandeep |
author_sort | Devabhakthuni, Sandeep |
collection | PubMed |
description | The objective of this review was to evaluate the clinical efficacy and safety of remifentanil in the management of labor pain. Although neuraxial analgesia is the best option during labor, alternative analgesic options are needed for patients with contraindications. Using a systematic literature search, clinical outcomes of remifentanil for labor pain have been summarized. Also, comparisons of remifentanil to other options including meperidine, epidural analgesia, fentanyl, and nitrous oxide are provided. Based on the literature review, remifentanil is associated with high overall maternal satisfaction and favorable side-effect profile. However, due to the low reporting of adverse events, large, randomized controlled trials are needed to evaluate maternal and neonatal safety adequately and determine the optimal dosing needed to provide effective analgesia. While remifentanil is a feasible alternative for patients who cannot or do not want to receive epidural analgesia, administration should be monitored closely for potential adverse effects. |
format | Online Article Text |
id | pubmed-3941183 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-39411832014-03-24 Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic Devabhakthuni, Sandeep Clin Med Insights Womens Health The objective of this review was to evaluate the clinical efficacy and safety of remifentanil in the management of labor pain. Although neuraxial analgesia is the best option during labor, alternative analgesic options are needed for patients with contraindications. Using a systematic literature search, clinical outcomes of remifentanil for labor pain have been summarized. Also, comparisons of remifentanil to other options including meperidine, epidural analgesia, fentanyl, and nitrous oxide are provided. Based on the literature review, remifentanil is associated with high overall maternal satisfaction and favorable side-effect profile. However, due to the low reporting of adverse events, large, randomized controlled trials are needed to evaluate maternal and neonatal safety adequately and determine the optimal dosing needed to provide effective analgesia. While remifentanil is a feasible alternative for patients who cannot or do not want to receive epidural analgesia, administration should be monitored closely for potential adverse effects. Libertas Academica 2013-05-06 /pmc/articles/PMC3941183/ /pubmed/24665213 http://dx.doi.org/10.4137/CMWH.S8015 Text en © 2013 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited. |
spellingShingle | Devabhakthuni, Sandeep Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic |
title | Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic |
title_full | Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic |
title_fullStr | Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic |
title_full_unstemmed | Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic |
title_short | Efficacy and Safety of Remifentanil as an Alternative Labor Analgesic |
title_sort | efficacy and safety of remifentanil as an alternative labor analgesic |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941183/ https://www.ncbi.nlm.nih.gov/pubmed/24665213 http://dx.doi.org/10.4137/CMWH.S8015 |
work_keys_str_mv | AT devabhakthunisandeep efficacyandsafetyofremifentanilasanalternativelaboranalgesic |