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Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease
This minireview provides current summaries of beta-blocker use in the management of hypertension and/or chronic kidney disease. Accumulated evidence suggests that atenolol is not sufficiently effective as a primary tool to treat hypertension. The less-than-adequate effect of beta-blockers in lowerin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941231/ https://www.ncbi.nlm.nih.gov/pubmed/24672712 http://dx.doi.org/10.1155/2014/919256 |
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author | Tomiyama, Hirofumi Yamashina, Akira |
author_facet | Tomiyama, Hirofumi Yamashina, Akira |
author_sort | Tomiyama, Hirofumi |
collection | PubMed |
description | This minireview provides current summaries of beta-blocker use in the management of hypertension and/or chronic kidney disease. Accumulated evidence suggests that atenolol is not sufficiently effective as a primary tool to treat hypertension. The less-than-adequate effect of beta-blockers in lowering the blood pressure and on vascular protection, and the unfavorable effects of these drugs, as compared to other antihypertensive agents, on the metabolic profile have been pointed out. On the other hand, in patients with chronic kidney disease, renin-angiotensin system blockers are the drugs of first choice for achieving the goal of renal protection. Recent studies have reported that vasodilatory beta-blockers have adequate antihypertensive efficacy and less harmful effects on the metabolic profile, and also exert beneficial effects on endothelial function and renal protection. However, there is still not sufficient evidence on the beneficial effects of the new beta-blockers. |
format | Online Article Text |
id | pubmed-3941231 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39412312014-03-26 Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease Tomiyama, Hirofumi Yamashina, Akira Int J Hypertens Review Article This minireview provides current summaries of beta-blocker use in the management of hypertension and/or chronic kidney disease. Accumulated evidence suggests that atenolol is not sufficiently effective as a primary tool to treat hypertension. The less-than-adequate effect of beta-blockers in lowering the blood pressure and on vascular protection, and the unfavorable effects of these drugs, as compared to other antihypertensive agents, on the metabolic profile have been pointed out. On the other hand, in patients with chronic kidney disease, renin-angiotensin system blockers are the drugs of first choice for achieving the goal of renal protection. Recent studies have reported that vasodilatory beta-blockers have adequate antihypertensive efficacy and less harmful effects on the metabolic profile, and also exert beneficial effects on endothelial function and renal protection. However, there is still not sufficient evidence on the beneficial effects of the new beta-blockers. Hindawi Publishing Corporation 2014 2014-01-30 /pmc/articles/PMC3941231/ /pubmed/24672712 http://dx.doi.org/10.1155/2014/919256 Text en Copyright © 2014 H. Tomiyama and A. Yamashina. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Tomiyama, Hirofumi Yamashina, Akira Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
title | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
title_full | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
title_fullStr | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
title_full_unstemmed | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
title_short | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
title_sort | beta-blockers in the management of hypertension and/or chronic kidney disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941231/ https://www.ncbi.nlm.nih.gov/pubmed/24672712 http://dx.doi.org/10.1155/2014/919256 |
work_keys_str_mv | AT tomiyamahirofumi betablockersinthemanagementofhypertensionandorchronickidneydisease AT yamashinaakira betablockersinthemanagementofhypertensionandorchronickidneydisease |