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NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice

BACKGROUND: Bone cancer pain (BCP) is one of the most disabling factors in patients suffering from primary bone cancer or bone metastases. Recent studies show several chemokines (for example, CCL2, CXCL10) in the spinal cord are involved in the pathogenesis of BCP. Here we investigated whether and h...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Zhu, Ming-Di, Zhang, Xin, Tian, Hao, Zhang, Jin-Hua, Wu, Xiao-Bo, Gao, Yong-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941254/
https://www.ncbi.nlm.nih.gov/pubmed/24580964
http://dx.doi.org/10.1186/1742-2094-11-38

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