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Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome

Background: Polycystic ovarian syndrome (PCOS) has been shown to cause a reduction in Health-related quality of life (HRQOL). Objective: This study examines the extent of different clinical symptoms in PCOS patients on HRQOL. Materials and Methods: A cross-sectional study was undertaken to ascertain...

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Autores principales: Bazarganipour, Fatemeh, Ziaei, Saeide, Montazeri, Ali, Foroozanfard, Fatemeh, Faghihzadeh, Soghrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Clinical Center for Infertility 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941412/
https://www.ncbi.nlm.nih.gov/pubmed/24639768
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author Bazarganipour, Fatemeh
Ziaei, Saeide
Montazeri, Ali
Foroozanfard, Fatemeh
Faghihzadeh, Soghrat
author_facet Bazarganipour, Fatemeh
Ziaei, Saeide
Montazeri, Ali
Foroozanfard, Fatemeh
Faghihzadeh, Soghrat
author_sort Bazarganipour, Fatemeh
collection PubMed
description Background: Polycystic ovarian syndrome (PCOS) has been shown to cause a reduction in Health-related quality of life (HRQOL). Objective: This study examines the extent of different clinical symptoms in PCOS patients on HRQOL. Materials and Methods: A cross-sectional study was undertaken to ascertain the factors related to HRQOL in 200 PCOS patients in Kashan, Iran. Main outcome measures were modified polycystic ovarian syndrome questionnaire (MPCOSQ) and clinical information of PCOS. Major clinical PCOS features including obesity (BMI), excessive body hair (hirsutism score), acne, menstrual cycle disturbances and infertility. Results: Findings showed that the most common HRQOL concern was menstrual irregularities and infertility, followed in descending order by hirsutism, weight, emotion, and acne. Multivariate analysis revealed the menstrual irregularities as a significant predictor of menstruation (p=0.005), emotion (p=0.02) and infertility (p=0.02) subscales of the MPCOSQ. Having of infertility, predicted scores on the infertility subscale (p<0.0001). Hirsutism score was a significant predictor of hirsutism (p<0.0001) and emotion (p<0.0001) subscales. Weight subscale concerns was predicted by BMI (p<0.0001), also, acne was found to be predicted score of acne subscale (p<0.0001). Conclusion: Worsened HRQOL in women with PCOS was related to more menstrual irregularities and infertility than to obesity. The finding suggests a potential for poorer compliance with weight management protocols among affected PCOS patients.
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spelling pubmed-39414122014-03-17 Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome Bazarganipour, Fatemeh Ziaei, Saeide Montazeri, Ali Foroozanfard, Fatemeh Faghihzadeh, Soghrat Iran J Reprod Med Background: Polycystic ovarian syndrome (PCOS) has been shown to cause a reduction in Health-related quality of life (HRQOL). Objective: This study examines the extent of different clinical symptoms in PCOS patients on HRQOL. Materials and Methods: A cross-sectional study was undertaken to ascertain the factors related to HRQOL in 200 PCOS patients in Kashan, Iran. Main outcome measures were modified polycystic ovarian syndrome questionnaire (MPCOSQ) and clinical information of PCOS. Major clinical PCOS features including obesity (BMI), excessive body hair (hirsutism score), acne, menstrual cycle disturbances and infertility. Results: Findings showed that the most common HRQOL concern was menstrual irregularities and infertility, followed in descending order by hirsutism, weight, emotion, and acne. Multivariate analysis revealed the menstrual irregularities as a significant predictor of menstruation (p=0.005), emotion (p=0.02) and infertility (p=0.02) subscales of the MPCOSQ. Having of infertility, predicted scores on the infertility subscale (p<0.0001). Hirsutism score was a significant predictor of hirsutism (p<0.0001) and emotion (p<0.0001) subscales. Weight subscale concerns was predicted by BMI (p<0.0001), also, acne was found to be predicted score of acne subscale (p<0.0001). Conclusion: Worsened HRQOL in women with PCOS was related to more menstrual irregularities and infertility than to obesity. The finding suggests a potential for poorer compliance with weight management protocols among affected PCOS patients. Research and Clinical Center for Infertility 2013-05 /pmc/articles/PMC3941412/ /pubmed/24639768 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Bazarganipour, Fatemeh
Ziaei, Saeide
Montazeri, Ali
Foroozanfard, Fatemeh
Faghihzadeh, Soghrat
Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome
title Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome
title_full Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome
title_fullStr Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome
title_full_unstemmed Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome
title_short Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome
title_sort health-related quality of life and its relationship with clinical symptoms among iranian patients with polycystic ovarian syndrome
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941412/
https://www.ncbi.nlm.nih.gov/pubmed/24639768
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