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Chromatin differentiation of white blood cells decreases DSB damage induction, prevents functional assembly of repair foci, but has no influence on protrusion of heterochromatic DSBs into the low-dense chromatin

Purpose: Higher order chromatin structure progressively changes with cell differentiation and seems to play an important role in DNA double-strand break (DSB) induction and repair (reviewed in [1]). We compared DNA damage in heterochromatin (Hc) upon the action of qualitatively different radiations....

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Detalles Bibliográficos
Autores principales:	Falk, Martin, Lukasova, Emilie, Falkova, Iva, Stefancikova, Lenka, Jezkova, Lucie, Bacikova, Alena, Davídková, Marie, Boreyko, Alla, Krasavin, Evgeny A., Kozubek, Stanislav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Poster Session 01: DNA Damage and Repair
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941545/ http://dx.doi.org/10.1093/jrr/rrt194

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