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Dependence of the yields of AP sites and AP clusters produced in plasmid DNA on scavenging capacity and LET

An apurinic or apyrimidinic site (AP site) has known to be one of the typical DNA lesions induced by ionizing irradiation to cells. A clustered DNA damage site composed of AP sites (AP clusters) can be visualized as a double-strand break (DSB) by a treatment of DNA sample with endonuclease IV protei...

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Detalles Bibliográficos
Autores principales: Shiina, Takuya, Watanabe, Ritsuko, Suzuki, Masao, Yokoya, Akinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941554/
http://dx.doi.org/10.1093/jrr/rrt160