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PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways

CDDP [cisplatin or cis-diamminedichloroplatinum(II)] and CDDP-based combination chemotherapy have been confirmed effective against gastric cancer. However, CDDP efficiency is limited because of development of drug resistance. In this study, we found that PAK4 (p21-activated kinase 4) expression and...

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Detalles Bibliográficos
Autores principales:	Fu, Xueqiong, Feng, Jiarui, Zeng, Duan, Ding, Yu, Yu, Changshou, Yang, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941610/ https://www.ncbi.nlm.nih.gov/pubmed/27919028 http://dx.doi.org/10.1042/BSR20130102

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