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Integrating water exclusion theory into βcontacts to predict binding free energy changes and binding hot spots
BACKGROUND: Binding free energy and binding hot spots at protein-protein interfaces are two important research areas for understanding protein interactions. Computational methods have been developed previously for accurate prediction of binding free energy change upon mutation for interfacial residu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941611/ https://www.ncbi.nlm.nih.gov/pubmed/24568581 http://dx.doi.org/10.1186/1471-2105-15-57 |