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Patterns and processes of somatic mutations in nine major cancers

BACKGROUND: Cancer genomes harbor hundreds to thousands of somatic nonsynonymous mutations. DNA damage and deficiency of DNA repair systems are two major forces to cause somatic mutations, marking cancer genomes with specific somatic mutation patterns. Recently, several pan-cancer genome studies rev...

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Detalles Bibliográficos
Autores principales:	Jia, Peilin, Pao, William, Zhao, Zhongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942057/ https://www.ncbi.nlm.nih.gov/pubmed/24552141 http://dx.doi.org/10.1186/1755-8794-7-11

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