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The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors
BACKGROUND: Mutant Ras oncogenes produce proteins that are unique to cancer cells and represent attractive targets for vaccine therapy. We have shown previously that vaccinating cancer patients with mutant ras peptides is feasible and capable of inducing a specific immune response against the releva...
Autores principales: | Rahma, Osama E, Hamilton, J Michael, Wojtowicz, Malgorzata, Dakheel, Omar, Bernstein, Sarah, Liewehr, David J, Steinberg, Seth M, Khleif, Samir N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942063/ https://www.ncbi.nlm.nih.gov/pubmed/24565030 http://dx.doi.org/10.1186/1479-5876-12-55 |
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