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Pharmacological characteristics and efficacy of a novel anti-angiogenic antibody FD006 in corneal neovascularization
BACKGROUND: Vascular endothelial growth factor (VEGF) is a key angiogenic factors. It plays an important role in both physiologic and pathologic angiogenesis and increases permeability across the vessels. Using antibody phage display technology, we obtained a novel anti-VEGFA IgG, named as FD006. In...
Autores principales: | Wang, Qun, Yang, Jing, Tang, Kun, Luo, Longlong, Wang, Liqiang, Tian, Lei, Jiang, Yanming, Feng, Jiannan, Li, Yan, Shen, Beifen, Lv, Ming, Huang, Yifei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942068/ https://www.ncbi.nlm.nih.gov/pubmed/24575750 http://dx.doi.org/10.1186/1472-6750-14-17 |
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