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Genetic Variant in MTRR, but Not MTR, Is Associated with Risk of Congenital Heart Disease: An Integrated Meta-Analysis
BACKGROUND: Congenital heart disease (CHD) is one of the most common birth defects and the leading cause of deaths among individuals with congenital structural abnormalities worldwide. Both Methionine synthase reductase (MTRR) and Methionine synthase (MTR) are key enzymes involved in the metabolic p...
Autores principales: | Cai, Bingxi, Zhang, Ti, Zhong, Rong, Zou, Li, Zhu, Beibei, Chen, Wei, Shen, Na, Ke, Juntao, Lou, Jiao, Wang, Zhenling, Sun, Yu, Liu, Lifeng, Song, Ranran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942359/ https://www.ncbi.nlm.nih.gov/pubmed/24595101 http://dx.doi.org/10.1371/journal.pone.0089609 |
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