Increased Glutamate Receptor and Transporter Expression in the Cerebral Cortex and Striatum of Gcdh (-/-) Mice: Possible Implications for the Neuropathology of Glutaric Acidemia Type I

We determined mRNA expression of the ionotropic glutamate receptors NMDA (NR1, NR2A and NR2B subunits), AMPA (GluR2 subunit) and kainate (GluR6 subunit), as well as of the glutamate transporters GLAST and GLT1 in cerebral cortex and striatum of wild type (WT) and glutaryl-CoA dehydrogenase deficient...

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Detalles Bibliográficos
Autores principales: Lagranha, Valeska Lizzi, Matte, Ursula, de Carvalho, Talita Giacomet, Seminotti, Bianca, Pereira, Carolina Coffi, Koeller, David M., Woontner, Michael, Goodman, Stephen I., de Souza, Diogo Onofre Gomes, Wajner, Moacir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942441/
https://www.ncbi.nlm.nih.gov/pubmed/24594605
http://dx.doi.org/10.1371/journal.pone.0090477

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