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Germline Transmission of an Embryonic Stem Cell Line Derived from BALB/c Cataract Mice
Mice embryonic stem (ES) cells have enabled the generation of mouse strains with defined mutation(s) in their genome for putative disease loci analysis. In the study of cataract, the complex genetic background of this disease and lack of long-term self-renewal ES cells have hampered the functional r...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942454/ https://www.ncbi.nlm.nih.gov/pubmed/24595217 http://dx.doi.org/10.1371/journal.pone.0090707 |