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Altering the Architecture of Tissue Engineered Hypertrophic Cartilaginous Grafts Facilitates Vascularisation and Accelerates Mineralisation
Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) can be leveraged to generate bone in vivo by executing an endochondral program, leading to increased interest in the use of such hypertrophic grafts for the regeneration of osseous defects. During normal skeletogenesis, canals with...
Autores principales: | Sheehy, Eamon J., Vinardell, Tatiana, Toner, Mary E., Buckley, Conor T., Kelly, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942470/ https://www.ncbi.nlm.nih.gov/pubmed/24595316 http://dx.doi.org/10.1371/journal.pone.0090716 |
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