The Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model

CYP3A4 metabolizes more than 50% of the drugs on the market. The large inter-individual differences of CYP3A4 expression may contribute to the variability of human drug responses. Post-transcriptional regulation of CYP3A4 is poorly understood, whereas transcriptional regulation has been studied much...

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Detalles Bibliográficos
Autores principales: Wei, Zhiyun, Jiang, Songshan, Zhang, Yiting, Wang, Xiaofei, Peng, Xueling, Meng, Chunjie, Liu, Yichen, Wang, Honglian, Guo, Luo, Qin, Shengying, He, Lin, Shao, Fengmin, Zhang, Lirong, Xing, Qinghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942699/
https://www.ncbi.nlm.nih.gov/pubmed/24594634
http://dx.doi.org/10.1038/srep04283

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