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Evidence for non-neutralizing autoantibodies against IL-10 signalling components in patients with inflammatory bowel disease
BACKGROUND: Inflammatory bowel disease constitutes a heterogeneous group of conditions, whose aetiology is only partly understood. The prevailing hypothesis on its pathogenesis is that IBD is the result of an inadequate immune response to the resident bacterial flora of the intestine. An autoimmune...
Autores principales: | Frede, Natalie, Glocker, Erik-Oliver, Wanders, Jennifer, Engelhardt, Karin R, Kreisel, Wolfgang, Ruemmele, Frank M, Grimbacher, Bodo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942769/ https://www.ncbi.nlm.nih.gov/pubmed/24581234 http://dx.doi.org/10.1186/1471-2172-15-10 |
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