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Evidence for non-neutralizing autoantibodies against IL-10 signalling components in patients with inflammatory bowel disease

BACKGROUND: Inflammatory bowel disease constitutes a heterogeneous group of conditions, whose aetiology is only partly understood. The prevailing hypothesis on its pathogenesis is that IBD is the result of an inadequate immune response to the resident bacterial flora of the intestine. An autoimmune...

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Detalles Bibliográficos
Autores principales: Frede, Natalie, Glocker, Erik-Oliver, Wanders, Jennifer, Engelhardt, Karin R, Kreisel, Wolfgang, Ruemmele, Frank M, Grimbacher, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942769/
https://www.ncbi.nlm.nih.gov/pubmed/24581234
http://dx.doi.org/10.1186/1471-2172-15-10

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