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Botulinum Toxin Complex Increases Paracellular Permeability in Intestinal Epithelial Cells via Activation of p38 Mitogen-Activated Protein Kinase

Clostridium botulinum produces a large toxin complex (L-TC) that increases paracellular permeability in intestinal epithelial cells by a mechanism that remains unclear. Here, we show that mitogen-activated protein kinases (MAPKs) are involved in this permeability increase. Paracellular permeability...

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Detalles Bibliográficos
Autores principales:	MIYASHITA, Shin-ichiro, SAGANE, Yoshimasa, INUI, Ken, HAYASHI, Shintaro, MIYATA, Keita, SUZUKI, Tomonori, OHYAMA, Tohru, WATANABE, Toshihiro, NIWA, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2013
Materias:	Bacteriology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942962/ https://www.ncbi.nlm.nih.gov/pubmed/23884081 http://dx.doi.org/10.1292/jvms.13-0164

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